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What is Crohn\'s Disease

The Basics of Crohn's Disease

What Is Crohn's Disease?

As you know, you eat food to get nutrients like protein and carbohydrates, which keep your body running. When your gastrointestinal (GI) tract processes that food, it absorbs the necessary nutrients and gets rid of any waste. The GI tract starts from your mouth and ends with your anus and includes your esophagus, stomach, and intestines.

When you have Crohn's disease (CD), your body's immune system begins attacking healthy cells in your GI tract, causing inflammation.

Intestines Diagram

Because it is caused by your immune system, CD is classified medically as an autoimmune disorder. This means that your body is producing antibodies that work against itself.

Other autoimmune disorders include rheumatoid arthritis, ulcerative colitis, psoriasis, psoriatic arthritis, and ankylosing spondylitis.

Specifically, CD is an inflammatory bowel disease, or IBD. Ulcerative colitis is also an IBD, but the inflammation is confined to the colon.

CD is most often found in a portion of the small intestine called the ileum. But unlike ulcerative colitis, CD can happen anywhere in your GI tract from the mouth to the anus.

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Crohn's Fact

What Causes Crohn's Disease?

Unfortunately, no one knows exactly what causes CD. All we know is that something in your body causes your immune system to overreact. Different stimuli may be the cause of CD in different people. For instance, it might be a kind of bacteria, something in your own intestines, or even your family history.

In fact, scientists now believe it is a combination of all these factors. If you have CD, you may have inherited a unique gene in your immune system. Then, something happened that triggered that gene, causing the overreaction, which then caused inflammation in your intestines.

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Who Gets Crohn's Disease?

CD can affect anyone at any age; however, it's usually first diagnosed in people in their teens and twenties.

CD tends to affect people of both sexes equally, though some groups, including blacks, whites, and Jews of European descent, are diagnosed more frequently than Asians and Hispanics.

Also, people who have family members with CD appear to be more likely to contract it themselves.

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Will Crohn's Ever Go Away?

Crohn's disease is a chronic condition, which means you have it for life. However, sometimes your disease may be in remission, with no symptoms at all.

Flare-ups can be caused by food, cigarettes, or stress, but they can also happen for no known reason at all.

Currently, there is no cure for CD, although advances are being made all the time. Often people need treatment to control symptoms and improve their quality of life.

In essence, CD can affect you and your life significantly—everything from your diet to your relationships to your choice of career.

But despite all this, it's important to remember that the majority of people with CD are able to live long and healthy lives.